Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1326854 | Journal of Organometallic Chemistry | 2007 | 5 Pages |
Abstract
The reaction of the cisplatin-vitamin B12 adduct [{B12}-CN-{cis-PtCl(NH3)2}]+ with iodide results in the rapid substitution of one chloride and one ammonia ligand by iodide and the formation of [{B12}-CN-{trans-PtI2(NH3)}]. The analogues reaction with 131I gave only mono-substitution and represents a straight forward way for platinum mediated radiolabeling of B12.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Pilar Ruiz-Sánchez, Stefan Mundwiler, Alfredo Medina-Molner, Bernhard Spingler, Roger Alberto,