| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1326854 | Journal of Organometallic Chemistry | 2007 | 5 Pages |
Abstract
The reaction of the cisplatin-vitamin B12 adduct [{B12}-CN-{cis-PtCl(NH3)2}]+ with iodide results in the rapid substitution of one chloride and one ammonia ligand by iodide and the formation of [{B12}-CN-{trans-PtI2(NH3)}]. The analogues reaction with 131I gave only mono-substitution and represents a straight forward way for platinum mediated radiolabeling of B12.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
![Iodination of cisplatin adduct of Vitamin B12 [{B12}-CN-{cis-PtCl(NH3)2}]+](/preview/png/1326854.png "First Page Preview: Iodination of cisplatin adduct of Vitamin B12 [{B12}-CN-{cis-PtCl(NH3)2}]+")
Authors
Pilar Ruiz-Sánchez, Stefan Mundwiler, Alfredo Medina-Molner, Bernhard Spingler, Roger Alberto,