The acetyl CoA synthase paradigm for hybrid bio-organometallics: Quantitative measures for resin-bound Ni-Rh complexes

Inspired by the active site of Acetyl CoA Synthase we have constructed the resin-bound ligand Ni(CGC)2− and derivatized it with RhI(CO)2. Through UV-Vis spectroscopy and Neutron Activation Analysis, the loading of CGC, Ni, and Rh have been established. The ability of O-Ni(CGC)Rh(CO)21- to withstand stress (i.e., leaching studies) was also investigated.