Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1327083 | Journal of Organometallic Chemistry | 2008 | 6 Pages |
A rhodium complex [ClRh(CO)(L1)] featuring a wide bite angle diphosphine ligand (L1 = 1,3-bis(2-diphenylphosphinomethylphenyl)benzene) has been synthesized and structurally characterized. L1 supports a bite angle (P–M–P angle, β) of 171.4° in the trans-square planar complex. L1 was tested in Rh-catalyzed 1,4-addition reactions of arylboronic acids (six examples) to α,β-unsaturated ketones (five examples). In mixed aqueous/cyclohexane solution at 60 °C, addition reactions proceed in up to quantitative yield with a 1:1 arylboronic acid/enone ratio. Yields as high as 77% can be acquired even when one of the coupling partners is sterically encumbered 2,4,6-trimethylphenylboronic acid.
Graphical abstractA terphspan Rh(I) complex has been prepared and structurally characterized. The terphspan ligand L1 has a wide bite angle of 171.37° in the [ClRh(CO)L1] complex. The terphspan ligand supports active catalysts for 1,4-addition of arylboronic acids to enones.Figure optionsDownload full-size imageDownload as PowerPoint slide