Titanium (IV) complexes based on substituted 2-[(2-hydroxyethyl)]aminophenols

Novel substituted 2-[(2-hydroxyethyl)]aminophenols, MeN(CHR1CR2R3OH)(C6H4-o-OH) (2–5), were synthesized by the reaction of 2-methylaminophenol with corresponding oxiranes. Titano-spiro-bis(ocanes) [MeN(CHR1CR2R3O)(C6H4-o-O)]2Ti 6–9 (2, 6, R1 = H, R2 = R3 = Me; 3, 7, R1 = R2 = Ph (treo-), R3 = H; 4, 8, R1 = Ph, R2 = R3 = H; 5, 9, R1 = R2 = H, R3 = Ph) based on [ONO]-ligands have been synthesized. The obtained compounds were characterized by 1H and 13C NMR spectroscopy and elemental analysis data. The complex [Ti(μ2-O){O-o-C6H4}{μ2-CMe2CH2}NMe]6 (10) was obtained by controlled hydrolysis of 6. Molecular structure of 10 was determined by X-ray structure analysis.

Graphical abstractNovel substituted 2-[(2-hydroxyethyl)]aminophenols were synthesized by the reaction of 2-methylaminophenol with different oxiranes. Titano-spiro-bis(ocanes) based on these ligands have been synthesized. The structure of obtained compounds was studied with 1H and 13C NMR spectroscopy. The structure of hydrolyse product of one of these ocanes was established by X-ray structure analysis.Figure optionsDownload full-size imageDownload as PowerPoint slide