| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1327121 | Journal of Organometallic Chemistry | 2010 | 8 Pages |
An insoluble polymer-supported phenyltin reagent was successfully used in Stille cross-coupling reactions with aryl- and heteroaryl-halides. Cross-coupling products were isolated in good to high yields with very low contamination by tin and palladium residues after removal of the residual supported organotin halide. The regeneration and recyclability of the supported phenyltin reagent were also examined and proved to be possible, but required palladium cleaning of the grafted polymer to be efficient along 4 cycles when Pd(PPh3)4 was used as catalyst.
Graphical abstractAn insoluble polymer-supported phenyltin was successfully used in Stille cross-coupling reactions with aryl- and heteroaryl-halides. Cross-coupling products were isolated in good to high yields with very low contamination by tin and palladium residues after removal of the residual supported organotin halide. The regeneration and recyclability of the supported phenyltin were also examined and proved to be possible after palladium cleaning of the grafted polymer.Figure optionsDownload full-size imageDownload as PowerPoint slide
