Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1327165 | Journal of Organometallic Chemistry | 2006 | 8 Pages |
Abstract
In this paper, we review our past and current efforts toward the elucidation of the biological chemistry of organotin compounds. In particular, we cover two prominent aspects of organotin compounds: their reactivity toward biological dithiols, and their degradation (or metabolization) mechanism using a combination of experimental and computational techniques.
Graphical abstractHydrolytic proteolysis of organotin model compounds.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Bethany A. Buck-Koehntop, Fernando Porcelli, John L. Lewin, Christopher J. Cramer, Gianluigi Veglia,