Chloro-diorganotin(IV) complexes of 4-methyl-1-piperidine carbodithioic acid: Synthesis, X-ray crystal structures, spectral properties and antimicrobial studies

Chloro-diorganotin(IV) complexes of 4-methyl-1-piperidine carbodithioic acid (4-MePCDTA) have been synthesized by the reaction with diorganotin dichloride in 1:1 molar ratio in anhydrous toluene. These newly synthesized complexes have been characterized by elemental, IR, multinuclear NMR (1H and 13C) and mass spectrometric studies. The crystal structures of complex 1 [Me2SnCl(4-MePCDT)] and 3 [Ph2SnCl(4-MePCDT)] have been determined by X-ray single crystal analysis, which show trigonal bipyramid geometry. These complexes were tested for their antimicrobial activity against six different plant and human pathogens. The screening results show that the complexes exhibit higher antibacterial and antifungal activity than the free ligand.

Graphical abstractThe synthesis of three new chlorodiorganotin(IV) complexes of 4-methyl-1-piperidine carbodithioic acid is reported. Their structural study was carried out by different spectroscopic methods and by single-crystal X-ray diffractometry for 1 and 3. The antimicrobial activity of the compounds is also reported.Figure optionsDownload full-size imageDownload as PowerPoint slide