| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1327231 | Journal of Organometallic Chemistry | 2005 | 7 Pages |
Abstract
The regioselectivity of Ni(0)-catalyzed cycloadditions of various isocyanates and asymmetrical alkynes to afford pyridones was explored. The use of PEt3 provided, in most cases, two of the four possible pyridone regioisomers in high overall yields. Mechanistic rationale for the product distribution is provided.
Graphical abstractThe regioselectivity of Ni(0)-catalyzed cycloadditions of various isocyanates and asymmetrical alkynes to afford pyridones was explored. The use of PEt3 provided, in most cases, two of the four possible pyridone regioisomers in high overall yields. Mechanistic rationale for the product distribution is provided.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Hung A. Duong, Janis Louie,