Intramolecular double or triple Suzuki coupling reaction of substituted di- or tribromobenzenes. An easy synthesis of fused tri- or tetracycles with a benzene core

Double or triple intramolecular Suzuki coupling reaction has been developed for the efficient synthesis of tri- or tetracyclic products with a benzene core in good yields. The reaction was realized via a one-pot procedure combining the hydroboration of the CC bond in the starting aryl halides and the intramolecular Suzuki coupling.

Graphical abstractDouble or triple intramolecular Suzuki coupling reaction has been developed for the efficient synthesis of tri- or tetracyclic products with a benzene core in good yields. The reaction was realized via a one-pot procedure combining the hydroboration of the CC bond in the starting aryl halides and the intramolecular Suzuki coupling.Figure optionsDownload full-size imageDownload as PowerPoint slide