Palladium-catalyzed carbonylative cross-coupling reaction of triarylantimony dicarboxylates with arylboronic acids: Synthesis of biaryl ketones

A novel palladium-catalyzed three-component carbonylative coupling reaction by use of triarylantimony diacetate, arylboronic acid and carbon monoxide (1 atm) could be attained under mild reaction conditions without any base as an additive. The reaction can be applied to a wide range of triarylantimony diacetates and boronic acids to afford the corresponding unsymmetrical biaryl ketones in good yields.

Graphical abstractThe reaction of triarylantimony diacetate with arylboronic acid under carbon monoxide (1 atm) atmosphere resulted in carbonylative cross-coupling reaction to afford unsymmetrical biaryl ketones in good yields. The reaction proceeds smoothly without any base as an additive and can be applied to a wide range of triarylantimony diacetates and boronic acids.Figure optionsDownload full-size imageDownload as PowerPoint slide