Article ID Journal Published Year Pages File Type
1328417 Journal of Organometallic Chemistry 2006 5 Pages PDF
Abstract

A novel cyclodextrin dimer bridged with titanocene moiety, titanocene di[mono[6-deoxy-6-(2-(thio-1,2-dicyane ethylenylthio)ethyl thio-1,2-dicyane ethylenylthio)]-β-cyclodextrin] (6), has been synthesized and characterized by IR spectroscopy, UV spectroscopy, thermogravimetry, MALDI-TOF MS spectrum, 1H and 13C NMR spectroscopy. Especially, its potent cytotoxity against Human Breast Cancer (MCF-7) has also been studied.

Graphical abstractA novel cyclodextrin dimer bridged with titanocene moiety has been synthesized and characterized. The introduction of the cyclodextrin into the titanocene compound remarkably increased its soluble and stable ability in water and the new compound demonstrated much higher cytotoxity against human breast cancer cells than titanocene dichloride.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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