Synthesis of chiral chelating N-heterocyclic carbene complexes of ruthenium

The first 9-membered chiral chelating bidentate imidazol-2-ylidene ruthenium (II) benzylidene complexes based on a cyclopentane backbone were synthesised and characterised via NMR and HRMS.

Graphical abstractThe first 9-membered chiral chelating bidentate imidazol-2-ylidene ruthenium (II) benzylidene complexes based on a cyclopentane backbone were synthesised by elaboration of a chiral cyclopentane dibromide to the bisimidazolium salt and then bisimidazolium-2-thione. Reduction of the thione functionality gave access to the bis(imidazol-2-ylidene), which when reacted with Grubbs catalyst affords the air stable chiral chelating bidentate NHC ruthenium benzylidene complexes.Figure optionsDownload full-size imageDownload as PowerPoint slide