Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1344762 | Tetrahedron: Asymmetry | 2010 | 6 Pages |
Abstract
The kinetic bioresolution of 2-nitrocyclohexanol 1 was investigated by screening a range of hydrolases both for enantioselective transesterification and for enantioselective hydrolysis of the corresponding acetate. By appropriate choice of biocatalyst and conditions, both enantiomers of cis and trans 2-nitrocyclohexanol 1 can be accessed in enantiopure form.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Sinead E. Milner, Maude Brossat, Thomas S. Moody, Curtis J. Elcoate, Simon E. Lawrence, Anita R. Maguire,