| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1344923 | Tetrahedron: Asymmetry | 2008 | 4 Pages |
Abstract
DNA-bound copper(II) complexes serve as catalysts for the hydrolytic kinetic resolution of 2-pyridyloxiranes in water. Selectivity factors of up to 2.7 were achieved, indicating a chirality transfer of DNA to epoxides via a coordinated metal ion.
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trans-2-[(2S,3S)-3-Phenyloxiranyl]pyridineC13H11NOEe = >95% ee[α]D20=-275 (c 3 × 10−3, EtOH)Source of chirality: preparative chiral HPLCAbsolute configuration: (2S,3S)
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Ewold W. Dijk, Ben L. Feringa, Gerard Roelfes,