| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1345020 | Tetrahedron: Asymmetry | 2008 | 5 Pages |
Abstract
A new chiral phosphine-phosphoramidite ligand (S)-HY-Phos 1 has been prepared from 1-naphthylamine via a two-step transformation, and successfully applied in the Rh-catalyzed asymmetric hydrogenation of various functionalized olefins, including α-(acetamido)cinnamates, enamides and α-enol ester phosphonates, in which up to 98% ee, 99% ee and 99% ee were achieved, respectively.
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N-[1-(8-Diphenylphosphino)naphthyl]-(S)-1,10-bi-2-naphthylphosphoramiditeC42H29NO2P2[α]D20=+53.7 (c 0.56, CHCl3)Source of chirality: (S)-BINOLAbsolute configuration: (S)
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Sai-Bo Yu, Jia-Di Huang, Dao-Yong Wang, Xiang-Ping Hu, Jun Deng, Zheng-Chao Duan, Zhuo Zheng,