| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1345224 | Tetrahedron: Asymmetry | 2015 | 6 Pages |
Novel optically active acridone bis(urea) and bis(thiourea) derivatives were synthesized and their enantiomeric recognition abilities towards the enantiomers of tetrabutylammonium salts of α-hydroxy and N-protected α-amino acids were examined in acetonitrile–DMSO 99:1 using fluorescence spectroscopy.
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1,1′-(9-Oxo-9,10-dihydroacridine-4,5-diyl)bis{3-[(1S)-1-phenylethyl]urea}C31H29N5O3Ee ⩾ 96%[α]D25 = −28 (c 0.15, DMF)Source of chirality: (S)-1-phenylethyl isocyanateAbsolute configuration: (S,S)
1,1′-(9-Oxo-9,10-dihydroacridine-4,5-diyl)bis{3-[(1S)-1-phenylethyl]thiourea}C31H29N5OS2Ee ⩾ 96%[α]D25 = −21 (c 0.15, DMF)Source of chirality: (S)-1-phenylethyl isothiocyanateAbsolute configuration: (S,S)
