| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1345364 | Tetrahedron: Asymmetry | 2007 | 5 Pages |
Abstract
We have developed a biocatalytic method to produce lactones and related compounds via the enzymatic hydrolysis of γ- and β-hydroxynitriles. The synthesis is a mild, general, and environmentally friendly way to enantioselectively hydrolyze nitriles with commercially available nitrilase enzymes. The synthesis of four pheromones is demonstrated via a one-step method.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Julie A. Pollock, Karen M. Clark, Bethany J. Martynowicz, Matthew G. Pridgeon, Matthew J. Rycenga, Kristen E. Stolle, Stephen K. Taylor,