| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1345431 | Tetrahedron: Asymmetry | 2007 | 6 Pages |
Chiral iridium Fc-PHOX complexes were readily prepared from Fc-PHOX, [Ir(cod)Cl]2 and NaBArF (or NaPF6) in high yields. They were applied as catalysts in the enantioselective hydrogenation of olefins to afford the corresponding products with high conversions and good enantioselectivities (up to 99% ee).
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-methyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC66H48BF24IrFeNOPEe = 100%[α]D20=-336.7 (c 0.28, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-isopropyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC68H52BF24FeIrNOPEe = 100%[α]D20=-471.2 (c 0.29, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-tert-butyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC69H54BF24FeIrNOPEe = 100%[α]D20=-641.1 (c 0.18, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-phenyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC71H50BF24FeIrNOPEe = 100%[α]D20=-578.0 (c 0.20, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-benzyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC72H52BF24FeIrNOPEe = 100%[α]D20=-397.4 (c 0.20, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
(η4-1,5-Cyclooctadiene) [(S,R)-(4,5-dihydro-4-tert-buty-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borateC69H54BF24FeIrNOPEe = 100%[α]D20=+217.2 (c 0.14, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,R)
(η4-1,5-Cyclooctadiene) [(S,S)-(4,5-dihydro-4-methyl-2-oxazolyl)-2-diphenylphosphinoferrocene] iridium(I) hexafluorophosphateC34H36F6FeIrNOP2Ee = 100%[α]D20=-160.1 (c 0.1, CH2Cl2)Source of chirality: asymmetric synthesisAbsolute configuration: (S,S)
