| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1345486 | Tetrahedron: Asymmetry | 2007 | 6 Pages |
Abstract
A series of oxazolidines have been prepared by reaction of either (1R,2S)-ephedrine or (1S,2S)-pseudoephedrine with salicylaldehyde derivatives. The resultant oxazolidines were used as catalytic ligands in the addition of diethylzinc to a variety of aromatic and aliphatic aldehydes. It was determined that the (1R,2S)-ephedrine based oxazolidine derivative 9 gave the highest enantioselectivities.
Related Topics
Physical Sciences and Engineering
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Authors
Raleigh W. II, Shawn R. Hitchcock,