| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1346097 | Tetrahedron: Asymmetry | 2012 | 4 Pages |
Abstract
An optimal hydrophobic ionic liquid was discovered as a solvent for highly enantioselective glyoxylate-ene reactions catalyzed by a chiral bis(oxazoline)–copper complex. The reactivity and stereoselectivity were highly dependent upon the property of the ionic liquids; reactions between olefins and ethyl glyoxylate in [Bmim]SbF6 at ambient temperature provided remarkably enhanced reactivity and stereoselectivity, which greatly exceed those of the corresponding reactions in dichloromethane. Furthermore, the metal–ligand complex was readily recycled up to eight times while exhibiting no significant decrease in reaction efficiency.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Mina Kim, Han Saem Jeong, Chang-Eun Yeom, B. Moon Kim,