| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1346282 | Tetrahedron: Asymmetry | 2013 | 19 Pages |
Abstract
Base-catalyzed reactions of silyl enolates with carbonyl compounds are an attractive variant of conventional directed aldol reactions. Over the past two decades, the reaction has gained prominence due to its inherent advantage for stereoselective manipulations. The present review provides a brief account of developments in this area. Various approaches are grouped together in order to provide the salient features of each conceptual development. It appears that the methods which generate nascent chiral enolates or cationic siliconium species have the biggest influence on the stereoselectivity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Revannath L. Sutar, Navalkishore N. Joshi,