| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1346333 | Tetrahedron: Asymmetry | 2011 | 6 Pages |
Abstract
A green and fully enzymatic procedure for the resolution of chiral alcohols through lipase/esterase-catalyzed acylation and subsequent lipase-catalyzed aminolysis using anhydrous ammonia was demonstrated. Both enantiomers can be obtained in high ee values (up to >99%) under ambient reaction conditions. The solvent and acyl donors can be recycled, and the enzyme can be reused for up to five times.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Bo Wang, Ling Jiang, Jue Wang, Jingbo Ma, Min Liu, Hongwei Yu,