| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1346387 | Tetrahedron: Asymmetry | 2011 | 4 Pages |
Abstract
An enantioselective synthesis of (R)- and (S)-3-amino-7-methyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one via an asymmetric reduction and spontaneous cyclisation is reported.
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(S)-3-Amino-7-methyl-3,4-dihydro-1H-[1,8]naphthyridin-2-oneC9H11N3O[α]D25=-82.1 (c 1.0021, water)Source of chirality: Precursor prepared via asymmetric hydrogenationAbsolute configuration: (S)
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
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Authors
Matthew Badland, Robert Carroll, Claire Chadwick, Joe WaiChiu Cheung, Steve Fussell, Daniel Laity, Philip Peach, David Shaw,