| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1346589 | Tetrahedron: Asymmetry | 2010 | 5 Pages |
Abstract
A concise synthesis of a tetrasaccharide related to the triterpenoid saponins Bellisoside has been accomplished from commercially available monosaccharides through rational protecting group manipulations and stereoselective glycosylations. For the glycosylation reactions, H2SO4-silica has been successfully used as an alternative to conventional Lewis acids such as TfOH or TMSOTf. The target tetrasaccharide has been synthesized in the form of its p-methoxyphenyl glycoside which leaves scope for further glyco-conjugate formation through the selective deprotection of p-methoxyphenyl glycoside followed by trichloroacetimidate chemistry.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Santanu Mandal, Nayan Sharma, Balaram Mukhopadhyay,