Enantioselective transesterification catalysis by Candida antarctica lipase immobilized on superparamagnetic nanoparticles

Lipase B from Candida antarctica can be directly immobilized onto functionalized superparamagnetic nanoparticles, preserving its enzymatic activity in the enantioselective transesterification of secondary alcohols, with excellent results in terms of enantiomeric discrimination. The immobilized enzyme can be easily recovered with a magnet, allowing its reuse with negligible loss of activity.

Graphical abstractLipase B from Candida antarctica immobilized on magnetic nanoparticles can be recycled many times, preserving its enzymatic activity in the transesterification of secondary alcohols.Figure optionsDownload full-size imageDownload as PowerPoint slide