| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1347571 | Tetrahedron: Asymmetry | 2009 | 5 Pages |
Abstract
The first catalytic asymmetric three-component reaction of ethyl glyoxylate, para-anisidine, and aliphatic, aromatic alkynes catalyzed by CuOTf·0.5C6H6/pybox 7 has been developed. The protocol provided the corresponding chiral β,γ-alkynyl α-amino acid derivatives in good yields and 66–74% ee.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Zhihui Shao, Xuewei Pu, Xiaojiao Li, Baomin Fan, Albert S.C. Chan,