Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1347641 | Tetrahedron: Asymmetry | 2008 | 4 Pages |
Abstract
The enantioselectivity for the reduction of ketones by Geotrichum candidum NBRC 5767 was improved upon immobilization of the whole cell onto an ion exchange resin with polyallylamine. Furthermore, immobilization of the cell enhanced the stability of the enzyme and enabled a continuous-flow reaction under normal aqueous conditions. The biocatalyst was also applied to the reaction in supercritical carbon dioxide.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Tomoko Matsuda, Ryo Marukado, Masaharu Mukouyama, Tadao Harada, Kaoru Nakamura,