Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1347707 | Tetrahedron: Asymmetry | 2008 | 4 Pages |
Abstract
An easy and efficient method for the microbial kinetic resolution of a substrate ethyl hydroxy(phenyl)methane(P-phenyl)phosphinate, which contains two stereogenic centers, is reported. To obtain the desired purpose biocatalyst, living fungal cells of Geotrichum candidum were cultivated with or without the supplementation of chemical additives influencing its activity. The biotransformation products were isolated with good yield and in enantiomerically pure forms.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Magdalena Klimek-Ochab, Ewa Żymańczyk-Duda, Małgorzata Brzezińska-Rodak, Paulina Majewska, Barbara Lejczak,