| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1348200 | Tetrahedron: Asymmetry | 2011 | 5 Pages |
Abstract
The direct catalytic enantioselective Henry (nitroaldol) reaction of isatins with nitromethane has been developed in the presence of a biscinchona alkaloid as a chiral organocatalyst. The resulting Henry adducts bearing C3-quaternary stereocentres were obtained in high yields (up to 94%) with high enantioselectivities (up to 97% ee).
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Parvathaneni Sai Prathima, Keesara Srinivas, Kodicherla Balaswamy, Racha Arundhathi, Gajjaia Narsimha Reddy, Balasubramanian Sridhar, Mandapati Mohan Rao, Pravin R. Likhar,