| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1348251 | Tetrahedron: Asymmetry | 2007 | 4 Pages |
Enantiospecific synthesis of 12-methoxyneorogiola-1,3,5,7(17),8-pentaene, containing the complete carbon framework of the natural diquinane diterpenes neorogioldiols, starting from (S)-campholenaldehyde is described.
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(1R,4R,5R)-4,7,8,8-Tetramethylbicyclo[3.3.0]oct-6-en-3-oneC12H18O[α]D22=-41.5 (c 5.9, CHCl3)Source of chirality: campholenaldehydeAbsolute configuration: (1R,4R,5R)
(1R,3S,4R,5R)-3-Methoxy-4,7,8,8-tetramethylbicyclo[3.3.0]oct-6-eneC13H22O[α]D23=-23.9 (c 16.2, CHCl3)Source of chirality: campholenaldehydeAbsolute configuration: (1R,3S,4R,5R)
(1R,5R,6R,7S)-7-Methoxy-2,2,6-trimethylbicyclo[3.3.0]oct-3-en-3-yl 4-methylphenyl ketoneC20H26O2[α]D25=-32.4 (c 5.1, CHCl3)Source of chirality: campholenaldehydeAbsolute configuration: (1R,5R,6R,7S)
(1R,5R,6R,7S)-7-Methoxy-2,2,6-trimethyl-3-[1-(4-methylphenyl)ethenyl]-bicyclo[3.3.0]oct-3-eneC21H28O[α]D24=-26.5 (c 2.0, CHCl3)Source of chirality: campholenaldehydeAbsolute configuration: (1R,5R,6R,7S)
