Cinchonine catalyzed diastereo- and enantioselective Michael addition of α-lithiated phosphonates to nitroalkenes

Conjugate addition of α-lithiated benzyl- and alkylphosphonates to a variety of aromatic and heteroaromatic nitroalkenes in the presence of 50 mol % of cinchonine–Li catalyst system proceeded in high yields, diastereo- and enantioselectivities in most cases.

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