| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1348477 | Tetrahedron: Asymmetry | 2006 | 5 Pages |
Abstract
Chiral ferrocene-containing pyrimidyl alkanol can be efficiently synthesized via asymmetric autocatalysis as an enantiomerically pure product. Moreover, a remarkable positive nonlinear effect occurs during this autocatalytic reaction. Starting from a nearly racemic seed, it is thus possible to produce a larger amount of the same compound with high ee.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
(S)-1-(2-Ferrocenylethynyl-5-pyrimidyl)-2-methylpropan-1-olC20H20FeN2OEe >99%[α]D18=-18.0 (c 0.99, CHCl3)Source of chirality: asymmetric autocatalysisAbsolute configuration: S
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
François Lutz, Tsuneomi Kawasaki, Kenso Soai,