| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1348489 | Tetrahedron: Asymmetry | 2006 | 4 Pages |
Abstract
The discovery and optimization of the highly enantioselective asymmetric hydrogenation of an α-alkoxy substituted ketone is described. The use of a ruthenium (phosphinoferrocenyl)oxazoline catalyst and the appropriate choice of a solvent and a base is the key to the success of this transformation.
Graphical abstractThe discovery and optimization of the highly enantioselective asymmetric hydrogenation of an α-alkoxy substituted ketone is described. The use of a ruthenium (phosphinoferrocenyl)oxazoline catalyst and the appropriate choice of a solvent and a base is the key to the success of this transformation.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
David M. Tellers, Matthew Bio, Zhiguo J. Song, J. Christopher McWilliams, Yongkui Sun,