| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1348580 | Tetrahedron: Asymmetry | 2007 | 8 Pages |
Abstract
An efficient biocatalytic process has been developed for the resolution of 1-(3â²-bromophenyl)ethylamine (RS)-1 by way of enantioselective lipase-mediated (R)-selective acylation with ethyl 2-methoxyacetate to afford (S)-amine (S)-1 and (R)-2â³-methoxyacetamide ((R)-2) in 91-95% and 90-92% isolated yield, respectively, and both with >99% ee.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Iqbal I. Gill, Jagbandhu Das, Ramesh N. Patel,