| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1349002 | Tetrahedron: Asymmetry | 2010 | 6 Pages |
Abstract
The diastereoselective fourfold addition to Ellman-type imines furnished after deprotection the tetrapodal amines in excellent yields. The unprecedented asymmetric fourfold addition of hydride and alkylzinc reagents to tetrapodal ketones and aldehydes, respectively, is achieved by employing CBS-reduction or [2.2]paracyclophane-based ketimine ligands with good to excellent global enantiomeric ratios.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Oliver Plietzsch, Christine Inge Schilling, Martin Nieger, Thierry Muller, Stefan Bräse,