| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1349063 | Tetrahedron: Asymmetry | 2007 | 4 Pages |
Abstract
Optimization of a new bienzymatic couple alcohol oxidase/peroxidase for the asymmetric oxidation of thioanisole was realized. The main advantages in the application of this system is the use of inexpensive and easily available enzymes and substrates, permitting gram scale enantioselective syntheses. Methanol, as a substrate for alcohol oxidase, also facilitates the solubilization of organic substrates in the reaction medium.
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Methyl-phenyl-sulfoxideC7H8OSEe = 75–78% eeSource of chirality: asymmetric enzymatic catalysisAbsolute configuration: (S)
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Fabio Pezzotti, Michel Therisod,