| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1349097 | Tetrahedron: Asymmetry | 2006 | 6 Pages |
Abstract
The enantioselective enzymatic desymmetrization (EED) of various 3-arylglutaric anhydrides 1 with alcohols in organic media has been studied. The effect of the solvent on the stereochemical outcome of the reaction was investigated in detail. The amount of biocatalyst was optimized, and the possibility of its re-use was tested. The first example of the EED of 3-substituted glutaric anhydrides with esters as nucleophiles is reported.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Anna Fryszkowska, Marta Komar, Dominik Koszelewski, Ryszard Ostaszewski,