| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1349417 | Tetrahedron: Asymmetry | 2005 | 6 Pages |
Abstract
The enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione 1 to either of the corresponding (R)- or (S)-6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-diones 2 and 3 is described.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
![Enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione](/preview/png/1349417.png "First Page Preview: Enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione")
Authors
Ramesh Patel, Linda Chu, Venkata Nanduri, Jianqing Li, Atul Kotnis, William Parker, Mark Liu, Richard Mueller,