| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1350734 | Tetrahedron: Asymmetry | 2006 | 4 Pages |
Abstract
Racemic Tröger base 1 can be readily obtained by the condensation of 4-toluidine and paraformaldehyde in the presence of Lewis acids and easily resolved via the preparation of diastereomeric aggregates using chiral dibenzoyl-l-tartaric acid 2.
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Tröger’s baseC17H18N2Ee ⩾98%[α]D25=-301 (c 0.22, hexane)Source of chirality: resolutionAbsolute configuration: (5R,11R)
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Sakilam Satishkumar, Mariappan Periasamy,