Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1350771 | Tetrahedron: Asymmetry | 2006 | 5 Pages |
Abstract
Bis-(3,5-dimethylphenyl)((S)-pyrrolidin-2-yl)methanol, easily prepared from l-proline, was found to be an efficient bifunctional organocatalyst, amongst the different 2-pyrrolidinemethanols tested, for the enantioselective Michael addition of malonate esters to nitroolefins. The products were isolated in good to high yields and with up to 56% ee.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Alessandra Lattanzi,