Article ID Journal Published Year Pages File Type
1354215 Biochemical Systematics and Ecology 2015 4 Pages PDF
Abstract

•O-Acetyl-7-methoxycamptothecin was reported as a new compound.•A new natural compound, 10-hydroxy-9-methoxycamptothecin, was reported.•The chemotaxonomic significance of Nothapodytes foetida and N. pittosporoides was discussed.•Mappicine and its derivatives as well as isocoumarins are key chemotaxonomic markers of the species.

A new alkaloid, O-acetyl-7-methoxycamptothecin (1), was isolated from the roots of Nothapodytes pittosporoides (Icacinaceae), together with seventeen known compounds (2–18). The structures of these compounds were identified by extensive spectroscopic interpretation. Isocoumarins were reported from the investigated genus for the first time. The alkaloids and isocoumarins in N. pittosporoides could serve as its chemotaxonomic markers.

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