Isoflavones and pterocarpans from Caragana changduensis

•First phytochemical investigation on Caragana changduensis Lion f. led to fifteen compounds.•Compounds 3, 5,9,10 and 12–14 were firstly obtained from genus Caragana.•The obtained constituents showed the relationships among the plants of genus Caragana.

Phytochemical investigation of the heartwoods of the stems of Caragana changduensis Lion f. led to the isolation and characterization of six isoflavones (1–6), four pterocarpans (7–10), three lignans (13–15), one chalcone (11), and one isoflavan (12). Among them, compounds 3, 5, 9, 10 and 12–14 were firstly obtained from genus Caragana. The chemotaxonomic significance of these compounds was summarized.