Article ID Journal Published Year Pages File Type
1355371 Bioorganic Chemistry 2007 10 Pages PDF
Abstract

Several Toyocamycin (4) analogues were examined for their ability to inhibit HCV RNA in a replicon assay. Among the compounds examined 4-methylthio (18) and 5-carboxamide oxime derivatives (23 and 27) of Toyocamycin were found to have good activity and selectivity.

Graphical abstractA series of Toyocamycin analogues were examined as potential anti-HCV agents.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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