| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1355896 | Bioorganic Chemistry | 2010 | 4 Pages |
Abstract
(−)-Neplanocin B, the natural isomer of a component of the neplanocin family was diasteroselectively synthesized from 2,3-O-isopropylidene-d-1,4-ribonolactone. However, when evaluated against several DNA and RNA viruses in cell culture experiments, it did not show any antiviral activity.
Graphical abstract(−)-Neplanocin B, the natural isomer of a component of the neplanocin family was diasteroselectively synthesized from 2,3-O-isopropylidene-D-1,4-ribonolactone.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nadège Hamon, Jean-Pierre Uttaro, Christophe Mathé, Christian Périgaud,