| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1356307 | Bioorganic Chemistry | 2006 | 11 Pages |
Abstract
CA199, a tryptamine analogue of fascaplysin, is a specific inhibitor of Cdk4-D1 in enzyme assays, blocks cancer cells at G0/G1 and prevents pRb hyperphosphorylation, but does not bind or intercalate DNA like fascaplysin.
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Authors
Sachin Mahale, Carine Aubry, Paul R. Jenkins, Jean-Didier Maréchal, Michael J. Sutcliffe, Bhabatosh Chaudhuri,