| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1356446 | Bioorganic Chemistry | 2009 | 5 Pages |
Abstract
The anticholinesterase activities of newly synthesized phosphorothioates and phosphorodithioates were investigated. The compounds were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition potency through IC50 determination. The selectivities of the synthesized compounds toward both enzymes were determined and compared in terms of their molecular structures.
Graphical abstractThe anticholinesterase activities of newly synthesized phosphorothioates and phosphorodithioates were investigated. The compounds were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition potency through IC50 determination.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Babak Kaboudin, Saeed Emadi, Atefeh Hadizadeh,