| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1360031 | Bioorganic & Medicinal Chemistry | 2009 | 4 Pages |
Abstract
A new oxylipin, 15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid (15-HTPE; 1) was isolated as an inhibitor of tube-formation from the soft coral Sinularia numerosa. Its structure was elucidated by means of spectral analysis and chemical degradation. 15-HTPE inhibited tube formation of EA.hy926 cells at the concentration of 20–40 μM.
Graphical abstractA new antiangiogenic oxylipin, 15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid (15-HTPE; 1) was isolated as an inhibitor of tube formation from the soft coral Sinularia numerosa. Its structure was elucidated by means of spectral analysis and chemical degradation.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Takahiro Yamashita, Yoichi Nakao, Shigeki Matsunaga, Tsutomu Oikawa, Yukimitsu Imahara, Nobuhiro Fusetani,