| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362326 | Bioorganic & Medicinal Chemistry | 2010 | 13 Pages |
Abstract
[d4U]-Spacer-[HI-236] bifunctional double-drug inhibitors against HIV-1 RT of the type shown below have been synthesized and evaluated in both cell-culture as well as in vitro against the enzyme, returning some nanomolar EC50 and IC50's.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![[d4U]-Spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase](/preview/png/1362326.png "First Page Preview: [d4U]-Spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase")
Authors
Yassir Younis, Roger Hunter, Clare I. Muhanji, Ian Hale, Rajinder Singh, Christopher M. Bailey, Todd J. Sullivan, Karen S. Anderson,