Article ID Journal Published Year Pages File Type
1384218 Carbohydrate Polymers 2009 7 Pages PDF
Abstract

Polysaccharides are widely used as carriers in the field of drug delivery. We present a methodology to obtain water soluble drug-conjugates based on scleroglucan. Selective C-6 halogenation gives access to C-6 esters; conjugates between methotrexate and scleroglucan are described, potentially useful for antitumour therapy or in rheumatoid arthritis treatment.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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