Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1384233 | Carbohydrate Research | 2012 | 6 Pages |
Abstract
An efficient one-pot synthesis of novel sugar based dispirooxindolo-pyrrolidines/pyrrolizidines has been accomplished by a [3+2]-cycloaddition. This method utilizes an azomethine ylide derived from isatin and sarcosine/l-proline, with an ether linked α-,β-unsaturated-β-C-glycosidic ketones as the dipolarophile. All these sugar-based heterocyclics were characterized by NMR (1H and 13C) and elemental analysis. Antimicrobial studies of sugar based dispiroheterocyclic compound 10 shows excellent activity against different microbes.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Arasappan Hemamalini, Subbiah Nagarajan, Thangamuthu Mohan Das,